Our services

Nos services
Born from the collaboration between NVH Medicinal® and the regional cancer center preclinical imaging platform, Engicare® proposes a wide-range of advanced customized research services, from recombinant protein conception to biological validation. With the use of advanced technologies dedicated to personalized medicine, our goal is to speed-up the development of recombinant proteins.

picto1 PROTEIN AND ANTIBODY ENGINEERING

  • Customized engineered-derivative or chimeric recombinant proteins
  • Conception of new engineered-protein using rational design (synthetic biology)
picto2 BIOPRODUCTION (Upstream process)

  • DNA vector construction
  • Protein production (mg-g) from bacteria or mammalian cells (HEK, CHO)
  • Stable cell line generation – Process optimization

BIOPRODUCTION (Downstream process)

  • Purification
  • Characterization
picto3 BIOLOGICAL ACTIVITY VALIDATION

  • In vitro ligand binding activity
  • In vitro assessment of bioactivity
  • Custom-tailored cell-based models
  • In vitro immunogenicity risk assessment
  • In vivo pharmacokinetics and biodistribution
picto4 PRECLINICAL EFFICACY

  • Proof of efficacy studies in a wide-range of experimental models of human pathologies
  • In vitro cell-disease models
  • In vivo animal models
  • Evaluation of customized imaging companion diagnostics
picto5 CLINICAL TRIAL

  • INCa accredited center of early phases clinical trials in oncology (Phase 1)
  • 20-25 % patients included in biomedical research studies

A dedicated team of experts on each domain is available to answer your need and to formulate the best proposal to your project. We also closely work with a team of clinicians, enhancing the transition to clinical trials. Our clients and partners can benefit from tax reduction since Engicare® has received the Research Tax Credit (CIR) accreditation.

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